info@medicampus.edu.mt
(+356) 7709 9274
Assoc. Prof. Bilyana Tacheva, PhD
Bilyana Tacheva, PhD, is Associate Professor of Biophysics at the Faculty of Medicine of Trakia University. Her research focuses on biological and model membrane systems, thermal dielectroscopy, drug–membrane interactions and bionanotechnologies. She also investigates erythrocyte membrane behaviour, haemoglobin properties, liposome stability and nanostructured systems for biomedical applications and drug delivery.
Education and Positions
2026–present
Associate Professor of Biophysics, Faculty of Medicine, Trakia University, Stara Zagora, Bulgaria.
2020–2026
Chief Assistant Professor in Physics, Department of Medical Physics, Biophysics, Roentgenology and Radiology, Faculty of Medicine, Trakia University.
2016
PhD in Biophysics, Department of Physics, Biophysics, Roentgenology and Radiology, Faculty of Medicine, Trakia University.
Thesis: Interactions of Pharmaceutical Substances and Nanoparticles with Model Membranes and Biomembranes.
2014–2020
Assistant Professor in Physics, Department of Medical Physics, Biophysics, Roentgenology and Radiology, Faculty of Medicine, Trakia University.
2000
Master’s Degree in Chemistry and Physics, Paisii Hilendarski University of Plovdiv, Bulgaria.
Qualification: Teacher of Chemistry and Physics.
1999
Master’s Degree in Chemistry and Physics, Paisii Hilendarski University of Plovdiv, Bulgaria.
Qualification: Teacher of Chemistry and Physics.
The Most Significant Publications
KARABALIEV, M.; PAARVANOVA, B.; SAVOVA, G.; TACHEVA, B.; et al. Redox potential of hemoglobin sub-micron particles and impact of layer-by-layer coating. International Journal of Molecular Sciences, 2025, 26: 7341.
KARABALIEV, M.; PAARVANOVA, B.; SAVOVA, G.; TACHEVA, B.; GEORGIEVA, R. In situ monitoring of morphology changes and oxygenation state of human erythrocytes during surfactant-induced hemolysis. Cells, 2025, 14: 469.
KARABALIEV, M.; TACHEVA, B.; PAARVANOVA, B.; GEORGIEVA, R. Change in osmotic pressure influences the absorption spectrum of hemoglobin inside red blood cells. Cells, 2024, 13: 589.
KARABALIEV, M.; PAARVANOVA, B.; SAVOVA, G.; TACHEVA, B.; JAHN, S.; GEORGIEVA, R. Electrochemical investigation of the stability of poly-phosphocholinated liposomes. Molecules, 2024, 29: 3511.
PAARVANOVA, B.; TACHEVA, B.; SAVOVA, G.; KARABALIEV, M.; GEORGIEVA, R. Hemolysis by saponin is accelerated at hypertonic conditions. Molecules, 2023, 28(20): 7096.
Professional Activities
Academic Activities
Associate Professor of Biophysics at the Faculty of Medicine, Trakia University.
Previous academic positions as Chief Assistant Professor and Assistant Professor in Physics within the Department of Medical Physics, Biophysics, Roentgenology and Radiology.
Research Activities
Research focused on biological and model membrane systems.
Investigation of membrane behaviour through thermal dielectroscopy.
Study of drug–membrane interactions and the effects of pharmaceutical substances and nanoparticles on biomembranes.
Research into erythrocyte membrane stability, haemolysis and haemoglobin behaviour.
Application of biophysical methods to bionanotechnologies and nanostructured systems.
Research Projects
Participation in research concerning synthetic oxygen carriers for allograft perfusion and transplantation.
Research on cell membrane-coated ROS-scavenging nanomaterials for inflammation modulation.
Participation in projects involving nanostructured surfaces for protein and cell sensing.
Research into protein nanocarriers for drug delivery.
Participation in national and bilateral scientific cooperation projects involving Bulgaria, China and Austria.
Scientific Memberships
Member of the Union of Physicists in Bulgaria.
Member of the Union of Scientists, Stara Zagora.
