The most significant publications

STANILOV, I.; GOSPODINOVA, K.; PETROV, V.; MITEVA, L.; TSACHEV, I.; STANILOVA, S. Enhanced production of IL-10 in PCR-positive dogs infected with E. canis and A. phagocytophilum facilitates specific immune responses. Microorganisms, 2024, 12: 2516.

MITEVA, L.; GRIGOROVA, A.; DIMITROVA, N.; et al. Anti-colon cancer activity of amino acid ester betulinates: apoptosis induction and IL1B gene expression in PBMCs by the lead compound. Pharmacia, 2024, 71: 1–5.

VASILEV, G.; VASILEVA, V.; IVANOVA, M.; et al. An elevated IL10 mRNA combined with lower TNFA mRNA level in active rheumatoid arthritis peripheral blood. Current Issues in Molecular Biology, 2024, 46(3): 2644–2657.

VALKANOV, S.; GRIGOROV, B.; GRIGOROVA, A.; PETROV, B.; YUSUF, R.; MITEVA, L. Sex-specific functional effect of IL-12 gene polymorphisms in brain tumours. Biotechnology & Biotechnological Equipment, 2024, 38(1).

STANILOV, I.; BLAZHEV, A.; MITEVA, L. Anaplasma and Ehrlichia species in Ixodidae ticks collected from two regions of Bulgaria. Microorganisms, 2023, 11(3): 594.

VASILEV, G.; IVANOVA, M.; STANILOV, I.; MITEVA, L.; STANILOVA, S.; MANOLOVA, I. Influence of IL10 and TGFB1 promoter polymorphisms on serum cytokine levels in the development and severity of rheumatoid arthritis. International Journal of Molecular Sciences, 2022, 23(19): 11955.

Professional Activities

Academic and Institutional Activities

Vice-Dean for Research Activities at the Faculty of Medicine, Trakia University.

Associate Professor of Molecular Biology at the Department of Molecular Biology, Immunology and Medical Genetics.

Administration and coordination of research activities within the Faculty of Medicine.

Participation in academic quality assurance, scientific projects and doctoral supervision.

Teaching Activities

Teaching Human Biology to medical students through lectures and practical classes in Bulgarian and English.

Teaching elective modules to students enrolled in Medicine.

Teaching Biology to students in Doctor’s Assistant and Assistant Pharmacist programmes.

Teaching Genetics to Midwifery students.

Supervision of PhD students in molecular biology, immunology and medical genetics.

Research Activities

Research focused on human gene polymorphisms and their functional effects.

Investigation of genetic predisposition, clinical manifestations and progression of immune-mediated diseases.

Study of gene-expression regulation at the transcriptional, translational and epigenetic levels.

Research into immunological status, immunomodulation and the biological effects of immunomodulators.

Investigation of signal-transduction pathways, transcription factors, cytokine synthesis, cell proliferation and apoptosis.

Research concerning rheumatoid arthritis, cancer biology, infectious diseases and host immune responses.

Scientific and Reviewing Activities

Participation in 31 scientific research projects.

Reviewer of scientific articles indexed in Web of Science.

Evaluator in procedures concerning scientific degrees and academic appointments.

Author of more than 80 scientific publications.

Professional Memberships

Member of the Bulgarian Society of Medical Biology.

Member of the Bulgarian Union of Scientists.

Member of the Bulgarian Society of Immunology.