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Assoc. Dr. Tsvetelin Georgiev, PhD

Trakia University

Tsvetelin Koychev Georgiev, MD, PhD, is Associate Professor of Physiology, Head of the Department of Physiology, Pathophysiology and Pharmacology, and Vice-Dean for Educational Affairs at the Faculty of Medicine of Trakia University. His research focuses on peptidergic regulation of visceral smooth muscle, experimental models of metabolic and organ injury, ferroptosis and oxidative stress. He also investigates the antioxidant potential of natural and synthetic compounds using EPR-based approaches.  

Education and Positions

2026–present

Vice-Dean for Educational Affairs, Faculty of Medicine, Trakia University, Stara Zagora, Bulgaria.

2024–present

Head of the Department of Physiology, Pathophysiology and Pharmacology, Faculty of Medicine, Trakia University.

2021–present

Associate Professor of Physiology, Department of Physiology, Pathophysiology and Pharmacology, Faculty of Medicine, Trakia University.

2017–2021

Chief Assistant Professor of Physiology, Department of Physiology, Pathophysiology and Pharmacology, Faculty of Medicine, Trakia University.

2012–2016

PhD in Animal and Human Physiology, Faculty of Medicine, Trakia University.

2011–2014

Specialisation in Physiology, Faculty of Medicine, Trakia University.

2009–2017

Assistant Professor of Physiology, Department of Physiology, Pathophysiology and Pharmacology, Faculty of Medicine, Trakia University.

2002–2008

Master’s Degree in Medicine, Faculty of Medicine, Trakia University.

The Most Significant Publications

PETKOVA-PARLAPANSKA, K.; STEFANOV, I.; ANANIEV, J.; et al. Sambucus nigra lyophilised fruit extract attenuated acute redox-homeostatic imbalance via mutagenic and oxidative stress modulation in a mouse model of gentamicin-induced nephrotoxicity. Pharmaceuticals, 2025, 18(1): 85.

GEORGIEV, T.; NIKOLOVA, G.; DYAKOVA, V.; et al. Antioxidant potential and oxidative stress modulation of Geranium macrorrhizum L. oil extract in gentamicin-induced nephrotoxicity. Pharmaceuticals, 2025, 18(9): 1283.

SHTEREVA, S.; GEORGIEV, T. Relationship between iron metabolism, ferroptosis and diabetes mellitus. Trakia Journal of Sciences, 2025, 23(3): 288–296.

HADZHIBOZHEVA, P.; PASHOVA-STOYANOVA, L.; TSOKEVA, Z.; et al. Appetite-regulating hormones in rats with fructose-induced metabolic changes. Pharmacia, 2023, 70(1): 1–7.

GEORGIEV, T.; NIKOLOVA, G.; DYAKOVA, V.; et al. Vitamin E and silymarin reduce oxidative tissue damage during gentamicin-induced nephrotoxicity. Pharmaceuticals, 2023, 16: 1365.

GEORGIEV, T.; HADZHIBOZHEVA, P.; KARAMALAKOVA, Y.; et al. Therapeutic approach of glutathione/glutathione peroxidase-4 axis modulation in the light of ferroptosis. Pharmacia, 2022, 69(3): 839–846.

Professional Activities

Academic and Teaching Activities

Vice-Dean for Educational Affairs at the Faculty of Medicine, Trakia University.

Head of the Department of Physiology, Pathophysiology and Pharmacology.

Associate Professor of Physiology with previous experience as Chief Assistant Professor and Assistant Professor.

Teaching Activities

Teaching activities in Physiology within the Faculty of Medicine, Trakia University.

Academic involvement in the Department of Physiology, Pathophysiology and Pharmacology.

Research Activities

Research focused on the peptidergic regulation of visceral smooth muscle contractility and reactivity.

Investigation of regulatory peptides including angiotensin II, vasopressin and ghrelin in urogenital and gastrointestinal systems.

Development of experimental animal models for metabolic disorders, organ injury and drug-induced toxicity.

Research into oxidative stress-driven cell-death mechanisms, with particular focus on ferroptosis.

Evaluation of natural and synthetic antioxidants in biological systems.

Experimental and Laboratory Activities

Use of in vitro and ex vivo models to investigate smooth muscle physiology.

Application of Electron Paramagnetic Resonance methods for evaluating antioxidant activity.

Experimental study of plant extracts, natural bioactive compounds and synthetic antioxidants.

Research into metabolic alterations, nephrotoxicity and oxidative tissue damage.

Scientific Production

Author or co-author of 48 scientific publications.

Research work covering physiology, oxidative stress, ferroptosis, antioxidant mechanisms and experimental pharmacology.

Professional Memberships

Member of the Bulgarian Medical Association.

Member of the Bulgarian Society of Physiological Sciences.

Member of the Bulgarian Peptide Society

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